STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

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Products

ELISA Kits (20)

Type

Cell-Based (1)

Cell-Based Phosphorylation (3)

Custom (3)

Development Kit (1)

DNA Binding (1)

Sandwich (10)

Sandwich CLIA (1)

Target

STAT3 (20)

Reactivity

Human (11)

Mouse (7)

Rat (8)

Bovine (1)

Chicken (1)

Monkey (1)

Pig (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (4)

96-Well Strip Plate (12)

Antibody Pair and Standard (1)

Publications

No (19)

Yes (1)

Sample Type

Adherent Cell Cultures (4)

Cell Culture Supernatants (3)

Cell Lysates (3)

EDTA Plasma (1)

Heparin Plasma (1)

Nuclear Lysates (1)

Plasma (8)

Serum (9)

Tissue Homogenates (4)

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Mouse/Human/Rat Phospho-STAT3 (Ser727) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1624

(4.0) Rating

(1) Publication(s)

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat Phospho-STAT3 (Tyr705) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1625

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$772

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Human STAT3 (Sandwich ELISA) ELISA Kit - LS-F54989

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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Human STAT3 (Sandwich ELISA) ELISA Kit - LS-F27241

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Mouse/Human/Rat STAT3 (DNA-Binding ELISA) ELISA Kit - LS-F819

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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Human STAT3 (Sandwich ELISA) ELISA Kit - LS-F12674

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$685

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Monkey STAT3 (Sandwich ELISA) ELISA Kit - LS-F48045

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rat STAT3 (Custom ELISA) ELISA Kit - LS-F18416

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$685

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Pig STAT3 (Custom ELISA) ELISA Kit - LS-F18417

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Chicken STAT3 (Custom ELISA) ELISA Kit - LS-F18418

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Human STAT3 (CLIA) ELISA Kit - LS-F30237

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse/Human/Rat STAT3 (Cell-Based ELISA) ELISA Kit - LS-F2328

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Rat STAT3 (Sandwich ELISA) ELISA Kit - LS-F27592

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Rat STAT3 (Sandwich ELISA) ELISA Kit - LS-F33378

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human STAT3 (Sandwich ELISA) ELISA Kit - LS-F33379

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse STAT3 (Sandwich ELISA) ELISA Kit - LS-F57301

Type:

Sandwich

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$795

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DevKit DuoPlus Human STAT3 ELISA Development Kit - LS-F71643

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,185; 1000 Wells/$1,751

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Mouse/Human/Rat Phospho-STAT3 (Tyr705) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F949

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$556

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Mouse STAT3 (Sandwich ELISA) ELISA Kit - LS-F12672

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$685

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Bovine STAT3 (Sandwich ELISA) ELISA Kit - LS-F12673

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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