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STAP2

signal transducing adaptor family member 2

STAP2 is the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants.

Gene Name: signal transducing adaptor family member 2
Synonyms: STAP2, BRK substrate, BKS, Brk kinase substrate, STAP-2, Breast tumor kinase substrate
Target Sequences: NM_017720 NP_060190.2 Q9UGK3

Publications (4)

1
STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation. Ikeda O, Miyasaka Y, Sekine Y, Mizushima A, Muromoto R, Nanbo A, Yoshimura A, Matsuda T. Biochemical and biophysical research communications. 2009 384:71-5. [PubMed:19393627] Related Antibodies: LS-B4920.
2
Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells. Sekine Y, Ikeda O, Tsuji S, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T. Journal of immunology (Baltimore, Md. : 1950). 2009 183:7966-74. [PubMed:19933863] Related Antibodies: LS-B4920.
3
Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells. Ikeda O, Sekine Y, Mizushima A, Nakasuji M, Miyasaka Y, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T. The Journal of biological chemistry. 2010 285:38093-103. [PubMed:20929863] [PMC:PMC2992243] Related Antibodies: LS-B4920.
4
Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells. Ikeda O, Mizushima A, Sekine Y, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T. Cancer science. 2011 102:756-61. [PubMed:21205088] Related Antibodies: LS-B4920.
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Products
Antibodies (19)
Primary (19)
STAP2 (19)
Human (18)
Mouse (3)
Rat (2)
Monkey (2)
IHC (10)
IHC-P (4)
WB (19)
ELISA (7)
ICC (1)
Peptide-ELISA (4)
rabbit (16)
goat (3)
Product Group
IHCPlus (2)
IgG (7)
polyclonal pc (19)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (11)
aa187-216 (7)
N-Terminus (4)
C Terminus (1)
Internal (1)
aa340-403 (1)
aa436-449 (1)
aa437-449 (1)
No (18)
Yes (1)
STAP2 Antibody - Anti-STAP2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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STAP2 Goat anti-Human Polyclonal (aa436-449) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
STAP2 Antibody - Anti-STAP2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
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STAP2 Goat anti-Human Polyclonal (aa437-449) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
STAP2 Antibody - IHC of paraffin-embedded BT483 xenograft using STAP2 antibody at 1:100 dilution.
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STAP2 Rabbit anti-Human Polyclonal (aa340-403) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
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STAP2 Rabbit anti-Human Polyclonal (aa187-216) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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STAP2 Rabbit anti-Human Polyclonal (aa187-216) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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STAP2 Rabbit anti-Human Polyclonal (aa187-216) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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STAP2 Rabbit anti-Human Polyclonal (aa187-216) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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STAP2 Rabbit anti-Human Polyclonal (aa187-216) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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STAP2 Rabbit anti-Human Polyclonal (aa187-216) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
STAP2 Antibody - STAP2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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STAP2 Rabbit anti-Human Polyclonal (aa187-216) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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STAP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
STAP2 Antibody - Antibody (1µg/ml) staining of Mouse fetal Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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STAP2 Goat anti-Mouse Polyclonal (C Terminus) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
100 µg/$503
STAP2 Antibody - Western blot analysis STAP-2 using HT29 whole cells lysates
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STAP2 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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STAP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
STAP2 Antibody - Western blot of STAP2 Antibody with human Fetal Lung lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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STAP2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
STAP2 Antibody - Western blot of STAP2 Antibody with human Fetal Lung lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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STAP2 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
STAP2 Antibody - Western blot of STAP2 Antibody with human Fetal Lung lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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STAP2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
STAP2 Antibody - Western blot of STAP2 Antibody with human Fetal Lung lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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STAP2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
STAP2 Antibody - Western blot analysis of STAP2 expression in HCT116 (A); SP2/0 (B); PC12 (C) whole cell lysates.
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STAP2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
Viewing 1-19 of 19 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).