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Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Gene Name: | stromal antigen 3 |
Synonyms: | STAG3, SCC3 homolog 3, Stromal antigen 3, Stromalin 3, Stromalin-3, Cohesin subunit SA-3 |
Target Sequences: | NM_012447 NP_036579.2 Q9UJ98 |
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