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STAG2

stromal antigen 2

Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.

Gene Name:	stromal antigen 2
Synonyms:	STAG2, Cohesin subunit SA-2, SCC3B, SCC3 homolog 2, Stromal antigen 2, SA2, BA517O1.1, SA-2
Target Sequences:	NM_006603 NP_006594.3 Q8N3U4

Publications (2)

Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium. Nicholson AM, Olpe C, Hoyle A, Thorsen AS, Rus T, Colombé M, Brunton-Sim R, Kemp R, Marks K, Quirke P, Malhotra S, Ten Hoopen R, Ibrahim A, Lindskog C, Myers MB, Parsons B, Tavaré S, Wilkinson M, Morrissey E, Winton DJ. Cell stem cell. 2018 June;22:909-918. (Human) [Full Text Article] [PubMed:29779891] [PMC:PMC5989058] Related Antibodies: LS-B11284.

A Diffusion-like Process Accommodates New Crypts During Clonal Expansion in Human Colonic Epithelium. Cora Olpe, Doran Khamis, Maria Chukanova, Nefeli Skoufou-Papoutsaki, Richard Kemp, Kate Marks, Cerys Tatton, Cecilia Lindskog, Anna Nicholson, Roxanne Brunton-Sim, Shalini Malhotra, Rogier Ten Hoopen, Rachael Stanley, Douglas J Winton, Edward Morrissey. Gastroenterology. 2021 Aug;;161:548-559.e23. [Full Text Article] [PubMed:33895166] [PMC:PMC8377717] Related Antibodies: LS-B11284.

STAG2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.

Human STAG2 Protein (Recombinant GST, N-terminus) (aa1130-1231) - LS-G61623

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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