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ST7L was identified by its similarity to the ST7 tumor suppressor gene found in the chromosome 7q31 region. This gene is clustered in a tail-to-tail manner with the WNT2B gene in a chromosomal region known to be deleted and rearranged in a variety of cancers. Several transcript variants encoding many different isoforms have been described, but some have not been fully characterized.
Gene Name: | Suppression Of Tumorigenicity 7 Like |
Synonyms: | ST7L, ST7-related protein, ST7R, STLR, Tumor suppressor ST7 like, FAM4B |
Target Sequences: | NM_017744 NP_060214.2 Q8TDW4 |
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