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ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

ST3GAL1 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet.

Gene Name:	ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Synonyms:	ST3GAL1, Alpha 2,3-ST 1, Gal-NAc6S, Sialyltransferase 4A, SIAT4-A, SIATFL, ST3GalA, ST3GalIA,1, ST3O, SIAT4, ST3GalA.1, ST3GalI, SIAT4A, ST3Gal I, ST3GalIA
Target Sequences:	NM_003033 NP_003024.1 Q11201

Publications (1)

Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-ß1-induced EMT and confers paclitaxel resistance in ovarian cancer. Wu X, Zhao J, Ruan Y, Sun L, Xu C, Jiang H. Cell death & disease. 2018 October;9:1102. [Full Text Article] [PubMed:30375371] [PMC:PMC6207573] Related Antibodies: LS-C185763.

Human ST3GAL1 (Custom ELISA) ELISA Kit - LS-F50734

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$672

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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