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ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

ST3GAL1 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet.

Gene Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Synonyms: ST3GAL1, Alpha 2,3-ST 1, Gal-NAc6S, Sialyltransferase 4A, SIAT4-A, SIATFL, ST3GalA, ST3GalIA,1, ST3O, SIAT4, ST3GalA.1, ST3GalI, SIAT4A, ST3Gal I, ST3GalIA
Target Sequences: NM_003033 NP_003024.1 Q11201

Publications (1)

1
Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-ß1-induced EMT and confers paclitaxel resistance in ovarian cancer. Wu X, Zhao J, Ruan Y, Sun L, Xu C, Jiang H. Cell death & disease. 2018 October;9:1102. [Full Text Article] [PubMed:30375371] [PMC:PMC6207573] Related Antibodies: LS-C185763.

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Antibodies (6)
Primary (6)
ST3GAL1 (6)
Human (6)
Mouse (1)
Rat (3)
Bat (3)
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Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (1)
IHC-P (1)
WB (6)
ICC (1)
rabbit (6)
IgG (5)
polyclonal pc (6)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (3)
aa254-303 (4)
aa1-195 (1)
No (5)
Yes (1)
ST3GAL1 Antibody - IHC of paraffin-embedded serous OVCA using ST3GAL1 antibody at 1:100 dilution.
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ST3GAL1 Rabbit anti-Human Polyclonal (aa1-195) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
ST3GAL1 Antibody - Western blot analysis of extracts of mouse liver, using ST3GAL1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 40s.
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ST3GAL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ST3GAL1 Antibody - Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ST3GAL1 Rabbit anti-Human Polyclonal (aa254-303) Antibody
Human
WB
Unconjugated
100 µl/$424
ST3GAL1 Antibody - Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ST3GAL1 Rabbit anti-Human Polyclonal (aa254-303) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ST3GAL1 Antibody - Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ST3GAL1 Rabbit anti-Human Polyclonal (aa254-303) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ST3GAL1 Antibody - Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ST3GAL1 Rabbit anti-Human Polyclonal (aa254-303) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).