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ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
| Gene Name: | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| Synonyms: | ST13, Aging-associated protein 2, AAG2, Hsc70-interacting protein, HSPABP1, HOP, Hsp70-interacting protein, HSPABP, FAM10A1, HIP, p48, PRO0786, Protein FAM10A1, Putative tumor suppressor ST13, SNC6, FAM10A4 |
| Target Sequences: | NM_003932 NP_003923.2 P50502 |
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