Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human alpha-signal sequence receptor gene (SSR1), also referred to as TRAP alpha, maps to the short arm of chromosome 6. SSR1 has several mRNA species as a result of complex alternative polyadenylation. SSR1 is unique in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.
|Gene Name:||signal sequence receptor, alpha|
|Synonyms:||SSR1, Signal sequence receptor, SSR-alpha, TRAP-alpha, TRAP alpha, Ssr, SSR alpha subunit, Trap-a, TRAPA|
|Target Sequences:||NM_003144 NP_003135.2 P43307|
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.