SSH1

slingshot protein phosphatase 1

SSH1 belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

SSH1 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (2)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (3)

Purification

Purified (1)

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SSH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128314

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.2 kDa

Price:

100 µg/$710

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Human SSH1 Protein (Recombinant GST) (Full Length) - LS-G33967

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

141.9 kDa

Price:

2 µg/$439

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Human SSH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92455

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.2 kDa

Price:

20 µg/$215

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Human SSH1 Protein (Recombinant GST, N-terminus) (aa950-1049) - LS-G62577

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SSH1 Protein (Recombinant GST, N-terminus) (aa752-849) - LS-G62579

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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