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SSH1

slingshot protein phosphatase 1

SSH1 belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: slingshot protein phosphatase 1
Family/Subfamily: Protein Phosphatase , Slingshot
Synonyms: SSH1, SSH-like protein 1, HSSH-1L, KIAA1298, Slingshot 1, SSH1L
Target Sequences: NM_018984 NP_061857.3 Q8WYL5

☰ Filters
Antibodies (18)
Proteins (5)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (18)
Recombinant (3)
Sandwich (1)
SSH1 (24)
Human (19)
IHC (3)
IHC-P (1)
WB (12)
Flo (2)
ELISA (13)
ICC (1)
IF (1)
IP (3)
Peptide-ELISA (1)
rabbit (15)
mouse (3)
IgG (14)
IgG1 (2)
IgG2a,k (1)
monoclonal mc (3)
polyclonal pc (15)
1A5C8 (1)
1D2 (1)
6C11G9 (1)
96-Well Strip Plate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
aa227-254 (7)
aa675-725 (1)
aa725-775 (1)
aa999-1049 (1)
No (24)
Tissue Homogenates (1)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (3)
Purified (1)
SSH1 Antibody - Immunofluorescence analysis of Hela cells using SLINGSHOT-1L mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher
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SSH1 Mouse anti-Human Monoclonal (1A5C8) Antibody
Human
ELISA, Flo, ICC, IHC
Unconjugated
100 µl/$459
SSH1 Antibody - Immunohistochemistry Dilution at 1:300 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Select
SSH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
SSH1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
SSH1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
SSH1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
SSH1 Antibody - Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SLINGSHOT-1L mouse mAb with DAB staining.
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SSH1 Mouse anti-Human Monoclonal (6C11G9) Antibody
Human
ELISA, Flo, IHC
Unconjugated
100 µl/$459
SSH1 Antibody - SSH1 monoclonal antibody (M02), clone 1D2. Western blot of SSH1 expression in HeLa.
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SSH1 Mouse anti-Human Monoclonal (1D2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
SSH1 Rabbit anti-Human Polyclonal (aa227-254) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
SSH1 Rabbit anti-Human Polyclonal (aa227-254) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SSH1 Rabbit anti-Human Polyclonal (aa227-254) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SSH1 Rabbit anti-Human Polyclonal (aa227-254) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SSH1 Rabbit anti-Human Polyclonal (aa227-254) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
SSH1 Rabbit anti-Human Polyclonal (aa227-254) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SSH1 Rabbit anti-Human Polyclonal (aa725-775) Antibody
Human
IP, WB
Unconjugated
100 µl/$448
Select
SSH1 Rabbit anti-Human Polyclonal (aa675-725) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
SSH1 Rabbit anti-Human Polyclonal (aa999-1049) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
SSH1 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SSH1 Antibody - SSH1 Antibody western blot of HeLa cell line lysates (35 ug/lane). The SSH1 antibody detected the SSH1 protein (arrow).
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SSH1 Rabbit anti-Human Polyclonal (aa227-254) Antibody
Human
WB
Unconjugated
400 µl/$393
SSH1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SSH1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SSH1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
77.2 kDa
20 µg/$215
SSH1 Protein - 12.5% SDS-PAGE of human SSH1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
141.9 kDa
2 µg/$439
SSH1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
77.2 kDa
100 µg/$710
SSH1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$834
Viewing 1-24 of 24 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).