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SS18L2
Synovial Sarcoma Translocation Gene On Chromosome 18-like 2
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L2 gene is homologous to SS18.[supplied by OMIM, Jul 2002]
| Gene Name: | Synovial Sarcoma Translocation Gene On Chromosome 18-like 2 |
| Synonyms: | SS18L2, KIAA-iso, SS18-like protein 2, SYT homolog 2 |
| Target Sequences: | NM_016305 NP_057389.1 Q9UHA2 |
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