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SRSF6 / SRP55
serine/arginine-rich splicing factor 6
Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.
| Gene Name: | serine/arginine-rich splicing factor 6 |
| Synonyms: | SRSF6, B52, Pre-mRNA-splicing factor SRP55, SFRS6, SR splicing factor 6, SRP55 |
| Target Sequences: | NM_006275 NP_006266.2 Q13247 |
Publications (4)
1
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, Smith DL, Faull RL, Roos RA, Howland D, Detloff PJ, Housman DE, Bates GP. Proceedings of the National Academy of Sciences of the United States of America. 2013 110:2366-70. (IP; Mouse)
[Full Text Article]
[PubMed:23341618]
[PMC:PMC3568346]
Related Antibodies: LS-B5712.
2
Overexpression of VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, leads to insufficient angiogenesis in patients with systemic sclerosis. Manetti M, Guiducci S, Romano E, Ceccarelli C, Bellando-Randone S, Conforti ML, Ibba-Manneschi L, Matucci-Cerinic M. Circulation research. 2011 109:e14-26. (ELISA; Human)
[Full Text Article]
[PubMed:21636803]
3
The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic ß-cells. Maria Inês Alvelos, Mirko Brüggemann, Fx Reymond Sutandy, Jonàs Juan-Mateu, Maikel Luis Colli, Anke Busch, Miguel Lopes, ngela Castela, Annemieke Aartsma-Rus, Julian König, Kathi Zarnack, Décio L Eizirik. Life science alliance. 2021 March;4: [Full Text Article]
[PubMed:33376132]
[PMC:PMC7772782]
Related Antibodies: LS-C290327.
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SRSF6 / SRP55
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SRSF6 / SRP55 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SRSF6 / SRP55 Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SRSF6 / SRP55 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SRSF6 / SRP55 Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SRSF6 / SRP55 Rabbit anti-Human Polyclonal (aa250-300) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
100 µl/$514
SRSF6 / SRP55 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SRSF6 / SRP55 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SRSF6 / SRP55 Mouse anti-Human Monoclonal (5G6) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SRSF6 / SRP55 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
SRSF6 / SRP55 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Wheat Germ Extract
GST, N-terminus
25 µg/$670; 10 µg/$479
293T Cells
Myc-DDK (Flag)
39.4 kDa
20 µg/$150
Wheat Germ Extract
GST
66 kDa
2 µg/$439
HEK 293 Cells
Myc-DDK (Flag)
39.4 kDa
100 µg/$494
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