LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

SRSF6 / SRP55

serine/arginine-rich splicing factor 6

Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.

Gene Name: serine/arginine-rich splicing factor 6
Synonyms: SRSF6, B52, Pre-mRNA-splicing factor SRP55, SFRS6, SR splicing factor 6, SRP55
Target Sequences: NM_006275 NP_006266.2 Q13247

Publications (3)

1
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, Smith DL, Faull RL, Roos RA, Howland D, Detloff PJ, Housman DE, Bates GP. Proceedings of the National Academy of Sciences of the United States of America. 2013 110:2366-70. (IP; Mouse) [Full Text Article] [PubMed:23341618] [PMC:PMC3568346] Related Antibodies: LS-B5712.
2
Overexpression of VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, leads to insufficient angiogenesis in patients with systemic sclerosis. Manetti M, Guiducci S, Romano E, Ceccarelli C, Bellando-Randone S, Conforti ML, Ibba-Manneschi L, Matucci-Cerinic M. Circulation research. 2011 109:e14-26. (ELISA; Human) [Full Text Article] [PubMed:21636803] Related Antibodies: LS-B3092.
3
Huntington's disease is a four-repeat tauopathy with tau nuclear rods. Fern[Character e1]ndez-Nogales M, Cabrera JR, Santos-Galindo M, Hoozemans JJ, Ferrer I, Rozemuller AJ, Hern[Character e1]ndez F, Avila J, Lucas JJ. Nature medicine. Aug;20:881-5. [Full Text Article] [PubMed:25038828] Related Antibodies: LS-B5712.

Filtered By: None
Target
SRSF6 / SRP55 (10)
Reactivity
Human (10)
Mouse (7)
Rat (6)
Bat (5)
Bovine (5)
Chimpanzee (3)
Gibbon (3)
Hamster (4)
Horse (5)
Monkey (5)
Pig (5)
Rabbit (5)
Zebrafish (4)
Application
IHC (6)
IHC-P (5)
WB (8)
ELISA (4)
IP (1)
Host
rabbit (9)
mouse (1)
Isotype
IgG (9)
IgG2b,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (9)
Clone
5G6 (1)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (7)
Epitope
aa143-192 (4)
30-110 aa, Internal (1)
aa250-300 (1)
Publications
No (8)
Yes (2)
Showing 1-10 of 10 results

SRSF6 / SRP55 Antibody (aa143-192) IHC-plus™ LS-B5712
Publications (2)
Publications (2)
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Bovine, Rat, Hamster, Human, Monkey
IHC IHC-P WB
Unconjugated
50µg  $485.00
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SRSF6 / SRP55 Antibody (aa143-192, HRP) LS-C440789
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Zebrafish, Rat, Hamster, Rabbit, Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SRSF6 / SRP55 Antibody (aa143-192, Biotin) LS-C440787
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Zebrafish, Rat, Hamster, Rabbit, Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SRSF6 / SRP55 Antibody (aa143-192, FITC) LS-C440788
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Zebrafish, Rat, Hamster, Rabbit, Mouse, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SRSF6 / SRP55 Antibody IHC-plus™ LS-B3092
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Rabbit, Bovine, Pig, Horse, Bat, Human, Monkey
ELISA IHC IHC-P
Unconjugated
50µg 0.15mg/ml  $425.00
Anti-SRSF6 / SFRS6 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-SRSF6 / SFRS6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-SRSF6 / SFRS6 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-SRSF6 / SFRS6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

SRSF6 / SRP55 Antibody (aa250-300) LS-C290327
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Mouse, Human
IP WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human and Mouse SRp55 by Western Blot (h and m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), Jurkat (J; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-SRp55 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. SRp55 was also immunoprecipitated by rabbit anti-SRp55 antibody BL13266, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).
Detection of Human and Mouse SRp55 by Western Blot (h and m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), Jurkat (J; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-SRp55 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. SRp55 was also immunoprecipitated by rabbit anti-SRp55 antibody BL13266, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

SRSF6 / SRP55 Antibody (30-110 aa, Internal) LS-C386185
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Mouse, Rat, Human
ELISA IHC
Unconjugated
100µl 1mg/ml  $265.00

SRSF6 / SRP55 Antibody (clone 5G6) LS-C139427
Mouse Monoclonal [clone 5G6] (IgG2b,k) to Human SRSF6 / SRP55
Human
ELISA WB
Unconjugated
100µg  $355.00
Western blot of SFRS6 expression in transfected 293T cell line by SFRS6 monoclonal antibody (M02), clone 5G6.
Detection limit for recombinant GST tagged SFRS6 is approximately 0.3 ng/ml as a capture antibody.
Western blot of SFRS6 expression in transfected 293T cell line by SFRS6 monoclonal antibody (M02), clone 5G6.
Detection limit for recombinant GST tagged SFRS6 is approximately 0.3 ng/ml as a capture antibody.

SRSF6 / SRP55 Antibody LS-C753181
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Human
ELISA WB
Unconjugated
100µg  $355.00

SRSF6 / SRP55 Antibody LS-C749604
Rabbit Polyclonal (IgG) to Human SRSF6 / SRP55
Mouse, Rat, Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of various cell lines, using SRSF6 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Western blot analysis of extracts of various cell lines, using SRSF6 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Showing 1-10 of 10 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy