SRPK2

SRSF protein kinase 2

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28. Can mediate hepatitis B virus (HBV) core protein phosphorylation. Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles.

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Products

Antibodies (22)

Proteins (11)

Type

Over-Expression Lysate (4)

Primary (22)

Recombinant (7)

Target

SRPK2 (33)

Reactivity

Human (22)

Mouse (11)

Rat (1)

Monkey (1)

Application

IHC (12)

IHC-P (2)

WB (18)

ELISA (9)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (22)

Isotype

IgG (12)

Clonality

polyclonal pc (22)

Format

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (10)

Epitope

aa380-617 (8)

aa465-495 (7)

aa425-475 (2)

Publications

No (33)

Tag

GST (4)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Human (9)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (5)

Purification

Purified (4)

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SRPK2 Antibody (aa465-495) LS-C99919

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa465-495) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SRPK2 Antibody (aa425-475) LS-C286890

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa425-475) Antibody

Reactivity:

Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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SRPK2 Antibody (aa465-495) LS-C330673

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa465-495) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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SRPK2 Antibody (aa465-495, Biotin) LS-C220782

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa465-495) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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SRPK2 Antibody (aa465-495, FITC) LS-C220784

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa465-495) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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SRPK2 Antibody (aa465-495, Azide-free, HRP) LS-C220785

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa465-495) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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SRPK2 Antibody (aa465-495, APC) LS-C220783

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa465-495) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SRPK2 Antibody (aa465-495, PE) LS-C220786

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa465-495) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

SRPK2 Antibody (aa425-475) LS-C289201

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa425-475) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SRPK2 Antibody LS-C808313

Antibody:

SRPK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SRPK2 Antibody LS-C830849

Antibody:

SRPK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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SRPK2 Antibody LS-C832366

Antibody:

SRPK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

SRPK2 Antibody LS-C780076

Antibody:

SRPK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

SRPK2 Antibody (aa380-617) LS-C374902

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa380-617) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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SRPK2 Antibody (aa380-617, HRP) LS-C713833

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa380-617) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

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SRPK2 Antibody (aa380-617, Biotin) LS-C688914

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa380-617) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

Select

SRPK2 Antibody (aa380-617, FITC) LS-C695947

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa380-617) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

Select

SRPK2 Antibody (aa380-617, APC) LS-C719011

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa380-617) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

SRPK2 Antibody (aa380-617, PE) LS-C727903

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa380-617) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

SRPK2 Antibody (aa380-617, APC, Cy7) LS-C736813

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa380-617) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676

Select

SRPK2 Antibody (aa380-617, Cy3) LS-C704819

Antibody:

SRPK2 Rabbit anti-Human Polyclonal (aa380-617) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE
• APC, Cy7
• More...
  • Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE
  • APC, Cy7
  • Cy3

Select

SRPK2 Antibody LS-C817359

Antibody:

SRPK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

Human SRPK2 Protein (Recombinant GST, N-terminus) (aa589-688) - LS-G60209

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

SRPK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104175

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.8 kDa

Price:

100 µg/$710

Select

Human SRPK2 Protein (Recombinant GST) (Full Length) - LS-G30534

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

101.42 kDa

Price:

10 µg/$479; 25 µg/$670

Viewing 1-25 of 33 product results

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