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SRGN / Serglycin

Serglycin

Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

Gene Name: Serglycin
Synonyms: SRGN, P.PG, Serglycin, Serglycin proteoglycan, PRG1, PPG, PRG
Target Sequences: NM_002727 NP_002718.2 P10124

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Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
SRGN / Serglycin (10)
No (10)
GST (2)
GST, N-terminus (1)
His (3)
His, N-Terminal (1)
His-Myc (1)
Myc-DDK (Flag) (2)
Human (8)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Human Cells (2)
Wheat Germ Extract (3)
Purified (4)
Low endotoxin level (2)
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
16.1 kDa
100 µg/$843
SRGN / Serglycin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SRGN / Serglycin Protein
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E. coli
His
15.4 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
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Wheat Germ Extract
GST
43.12 kDa
10 µg/$479; 25 µg/$670
SRGN / Serglycin Protein - 12.5% SDS-PAGE of human SRGN stained with Coomassie Blue
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Wheat Germ Extract
GST
44.1 kDa
2 µg/$439
SRGN / Serglycin Protein - Recombinant Serglycin (SRGN) by SDS-PAGE
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E. coli
His, N-Terminal
22kDa
10 µg/$260; 50 µg/$335; 200 µg/$622; 100 µg/$497; 1 mg/$1,588; 500 µg/$1,185; 5 mg/$2,522; 2 mg/$1,760
SRGN / Serglycin Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
SRGN / Serglycin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
17.62 kDa
20 µg/$150
Select
Human Cells
His-Myc
Less than 1.0 EU/µg protein (determined by LAL method).
17.3 kDa
100 µg/$721
SRGN / Serglycin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
17.62 kDa
100 µg/$494
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).