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SRD5A2

steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

Steroid 5-alpha reductase 2 is a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. This isoform is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).

Gene Name: steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
Synonyms: SRD5A2, 5 alpha-SR2, S5AR 2, Type II 5-alpha reductase, SR type 2, Steroid 5-alpha-reductase 2
Target Sequences: NM_000348 NP_000339.2 P31213

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Proteins (1)
Recombinant (1)
SRD5A2 (1)
No (1)
GST, N-terminus (1)
Human (1)
Wheat Germ Extract (1)
SRD5A2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).