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Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
Gene Name: | SRC kinase signaling inhibitor 1 |
Synonyms: | SRCIN1, KIAA1684, p140Cap, SNAP-25-interacting protein, SNIP, SNAP25-interacting protein, p130Cas-associated protein, p140 |
Target Sequences: | AF156982 NP_079524.2 Q9C0H9 |
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