SQSTM1

sequestosome 1

Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels.

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Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

SQSTM1 (8)

Publications

No (8)

Tag

GST (1)

His (2)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human SQSTM1 Protein (Recombinant His) - LS-G762

Source:

E. coli

Tag:

His

Price:

100 µg/$342; 500 µg/$641; 20 µg/$254

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SQSTM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125858

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.69 kDa

Price:

100 µg/$494

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Human SQSTM1 Protein (Recombinant GST) (Full Length) - LS-G31382

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

74.14 kDa

Price:

10 µg/$479; 25 µg/$670

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Human SQSTM1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68157

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.5 kDa

Price:

20 µg/$1,107

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Human SQSTM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81568

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.5 kDa

Price:

20 µg/$150

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Human SQSTM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81569

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.69 kDa

Price:

20 µg/$150

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SQSTM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100169

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.5 kDa

Price:

100 µg/$494

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Human SQSTM1 Protein (Recombinant His) (aa136-400) - LS-G15220

Source:

E. coli

Tag:

His

Molecular Weight:

29.8 kDa

Price:

10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136

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