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SPY1 / SPDYA
speedy/RINGO cell cycle regulator family member A
Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1, CDK2 and CDKN1B/KIP1. Can activate CDK2 without promoting CDK2 phosphorylation. Mediates cell survival during the DNA damage process through activation of CDK2.
| Gene Name: | speedy/RINGO cell cycle regulator family member A |
| Synonyms: | SPDYA, RINGO3, SPDY1, Speedy homolog 1 (Drosophila), Speedy-1, Speedy protein A, HSpy/Ringo A, RINGO A, RINGOA, SPY1 |
| Target Sequences: | NM_182756 NP_877433.2 Q5MJ70 |
Publications (2)
1
The cyclin-dependent kinase activator, Spy1A, is targeted for degradation by the ubiquitin ligase NEDD4. Al Sorkhy M, Craig R, Market B, Ard R, Porter LA. The Journal of biological chemistry. 2009 284:2617-27.
[PubMed:19054764]
2
The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancer. Al Sorkhy M, Ferraiuolo RM, Jalili E, Malysa A, Fratiloiu AR, Sloane BF, Porter LA. BMC cancer. 2012 12:45.
[PubMed:22280365]
[PMC:PMC3294245]
☰ Filters
Products
Antibodies
(20)
Type
Primary
(20)
Target
SPY1 / SPDYA
(20)
Reactivity
Human
(20)
Mouse
(11)
Rat
(7)
Chimpanzee
(3)
Gibbon
(3)
Pig
(3)
Sheep
(1)
Application
IHC
(3)
WB
(19)
ELISA
(1)
ICC
(1)
IF
(4)
IP
(1)
Peptide-ELISA
(1)
Host
rabbit
(20)
Isotype
IgG
(13)
Clonality
polyclonal pc
(20)
Format
Biotin Conjugated
(3)
DY488 Conjugated
(1)
DY550 Conjugated
(1)
DY650 Conjugated
(1)
FITC Conjugated
(2)
HRP Conjugated
(2)
Unconjugated
(10)
Epitope
C-Terminus
(8)
N-Terminus
(4)
aa200-286
(1)
Publications
No
(20)
SPY1 / SPDYA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SPY1 / SPDYA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
SPY1 / SPDYA Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321
SPY1 / SPDYA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SPY1 / SPDYA Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SPY1 / SPDYA Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
20 µl/$275; 100 µl/$389
SPY1 / SPDYA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP
Unconjugated
100 µg/$341
SPY1 / SPDYA Rabbit anti-Human Polyclonal (aa200-286) Antibody
Mouse, Human
WB
Unconjugated
0.1 ml/$386
SPY1 / SPDYA Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Sheep, Rat, Human
WB
Biotin Conjugated
0.1 ml/$416
SPY1 / SPDYA Rabbit anti-Human Polyclonal (C-Terminus) (DY650) Antibody
Mouse, Human
WB
DY650 Conjugated
0.1 ml/$416
SPY1 / SPDYA Rabbit anti-Human Polyclonal (C-Terminus) (DY488) Antibody
Mouse, Human
WB
DY488 Conjugated
0.1 ml/$416
SPY1 / SPDYA Rabbit anti-Human Polyclonal (C-Terminus) (DY550) Antibody
Mouse, Human
WB
DY550 Conjugated
0.1 ml/$416
SPY1 / SPDYA Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
SPY1 / SPDYA Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Rat, Pig, Gibbon, Human
WB
HRP Conjugated
100 µl/$469
SPY1 / SPDYA Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Rat, Pig, Gibbon, Human
WB
Biotin Conjugated
100 µl/$469
SPY1 / SPDYA Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Rat, Pig, Gibbon, Human
WB
FITC Conjugated
100 µl/$469
SPY1 / SPDYA Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
SPY1 / SPDYA Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
SPY1 / SPDYA Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
SPY1 / SPDYA Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
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