SPTLC3 / C20orf38

serine palmitoyltransferase, long chain base subunit 3

The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT; EC 2.3.1.50), which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al., 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3), depending on the tissue in which biosynthesis occurs (Hornemann et al., 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit, SSSPTA (MIM 613540) and SSSPTB (MIM 610412), that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al., 2009 [PubMed 19416851]).

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Proteins (2)

Type

Recombinant (2)

Target

SPTLC3 / C20orf38 (2)

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No (2)

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His-T7 (2)

Species

Human (1)

Mouse (1)

Source

E. coli (2)

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Human SPTLC3 / C20orf38 Protein (Recombinant His-T7) (aa238-552) - LS-G25847

Source:

E. coli

Tag:

His-T7

Molecular Weight:

38.7 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Mouse SPTLC3 / C20orf38 Protein (Recombinant His-T7) (aa80-563) - LS-G25848

Source:

E. coli

Tag:

His-T7

Molecular Weight:

58.4 kDa

Price:

10 µg/$285; 50 µg/$467; 100 µg/$747; 200 µg/$932; 1 mg/$2,058; 500 µg/$1,590; 5 mg/$3,263; 2 mg/$2,246

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