SPTBN2

spectrin, beta, non-erythrocytic 2

Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

SPTBN2 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human SPTBN2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114973

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

271.1 kDa

Price:

100 µg/$710

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Human SPTBN2 Protein (Recombinant GST, N-terminus) (aa643-720) - LS-G60199

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SPTBN2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86948

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

271.1 kDa

Price:

20 µg/$215

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