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SPRY2 / Sprouty 2
sprouty homolog 2 (Drosophila)
SPRY2 / Sprouty 2 is a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
| Gene Name: | sprouty homolog 2 (Drosophila) |
| Synonyms: | SPRY2, HSPRY2, Protein sprouty homolog 2, Sprouty homolog 2 (Drosophila), Sprouty 2, Spry-2, Sprouty (Drosophila) homolog 2 |
| Target Sequences: | NM_005842 NP_005833.1 O43597 |
Publications (2)
1
Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2. Zhang C, Chaturvedi D, Jaggar L, Magnuson D, Lee JM, Patel TB. Arteriosclerosis, thrombosis, and vascular biology. 2005 25:533-8.
[PubMed:15653567]
2
A coordinated progression of progenitor cell states initiates urinary tract development. Oraly Sanchez-Ferras, Alain Pacis, Maria Sotiropoulou, Yuhong Zhang, Yu Chang Wang, Mathieu Bourgey, Guillaume Bourque, Jiannis Ragoussis, Maxime Bouchard. Nature communications. 2021 May;12:2627. [Full Text Article]
[PubMed:33976190]
[PMC:PMC8113267]
Related Antibodies: LS-C499867.
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SPRY2 / Sprouty 2
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(1)
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$515
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
![SPRY2 / Sprouty 2 Antibody - Immunoperoxidase of monoclonal antibody to SPRY2 on formalin-fixed paraffin-embedded human lymphoma. [antibody concentration 3 ug/ml].](https://lsbio-7d62.kxcdn.com/image2/spry2-sprouty-2-antibody-clone-1e10-ls-c133632/52368_5011524.jpg)
SPRY2 / Sprouty 2 Mouse anti-Human Monoclonal (1E10) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa107-156) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa107-156) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa107-156) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SPRY2 / Sprouty 2 Rabbit anti-Mouse Polyclonal (aa116-305) Antibody
Mouse
WB
Unconjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
25 µl/$304
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa116-305) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$973
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa6-35) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa6-35) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa6-35) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa6-35) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa6-35) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa6-35) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa26-39) Antibody
Mouse, Dog, Rat, Hamster, Pig, Human
WB
Unconjugated
200 µg/$820
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa6-35) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SPRY2 / Sprouty 2 Goat anti-Human Polyclonal (aa1-175) Antibody
Mouse, Human
WB
Unconjugated
100 µg/$941
SPRY2 / Sprouty 2 Rabbit anti-Human Polyclonal (aa75-125) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
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