SPPL2A / IMP3

signal peptide peptidase like 2A

Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. Also responsible for the intramembrane cleavage of Fas antigen ligand FASLG, which promotes the release of the intracellular FasL domain (FasL ICD). May play a role in the regulation of innate and adaptive immunity.

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Products

Antibodies (13)

Proteins (1)

Type

Primary (13)

Recombinant (1)

Target

SPPL2A / IMP3 (14)

Reactivity

Human (13)

Mouse (1)

Rat (1)

Application

IHC (8)

IHC-P (1)

WB (9)

ELISA (11)

Host

rabbit (13)

Isotype

IgG (12)

Clonality

polyclonal pc (13)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (5)

Epitope

aa108-138 (7)

Publications

No (14)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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SPPL2A / IMP3 Antibody (aa108-138) LS-C100059

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (aa108-138) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SPPL2A / IMP3 Antibody (aa108-138) LS-C330670

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (aa108-138) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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SPPL2A / IMP3 Antibody (aa108-138, Biotin) LS-C220759

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (aa108-138) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SPPL2A / IMP3 Antibody (aa108-138, FITC) LS-C220760

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (aa108-138) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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SPPL2A / IMP3 Antibody (aa108-138, PE) LS-C220762

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (aa108-138) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

SPPL2A / IMP3 Antibody (aa108-138, APC) LS-C220758

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (aa108-138) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SPPL2A / IMP3 Antibody (aa108-138, Azide-free, HRP) LS-C220761

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (aa108-138) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

Select

SPPL2A / IMP3 Antibody LS-C751656

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

SPPL2A / IMP3 Antibody LS-C397305

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPPL2A / IMP3 Antibody (HRP) LS-C397927

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPPL2A / IMP3 Antibody (Biotin) LS-C397931

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPPL2A / IMP3 Antibody (FITC) LS-C397928

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SPPL2A / IMP3 Antibody LS-C750508

Antibody:

SPPL2A / IMP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

Human SPPL2A / IMP3 Protein (Recombinant GST, N-terminus) (aa31-129) - LS-G63413

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Viewing 1-14 of 14 product results

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