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SPON2 / MINDIN

spondin 2, extracellular matrix protein

Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens By similarity. Binds bacterial lipopolysaccharide (LPS).

Gene Name: spondin 2, extracellular matrix protein
Synonyms: SPON2, DIL-1, DIL1, M-SPONDIN, Spondin-2, MINDIN
Target Sequences: NM_012445 NP_036577.1 Q9BUD6

Publications (1)

1
Mindin deficiency alleviates renal fibrosis through inhibiting NF-?B and TGF-ß/Smad pathways. Kang Yang, Wei Li, Tao Bai, Yusha Xiao, Weimin Yu, Pengcheng Luo, Fan Cheng. Journal of cellular and molecular medicine. 2020 May;24:5740-5750. [Full Text Article] [PubMed:32253812] [PMC:PMC7214143]

☰ Filters
Products
Proteins (13)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (5)
Recombinant (7)
SPON2 / MINDIN (13)
No (13)
6His, C-terminus (2)
6His, N-terminus (3)
GST (1)
His-GST (1)
His-T7 (2)
Myc-DDK (Flag) (4)
Human (9)
Mouse (1)
Rat (1)
293T Cells (2)
E. coli (4)
HEK 293 Cells (4)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.4kD
10 µg/$266; 50 µg/$343; 500 µg/$1,377; 1 mg/$1,765
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.4 kDa
10 µg/$266; 50 µg/$339
SPON2 / MINDIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
35.6 kDa
20 µg/$150
SPON2 / MINDIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
35.6 kDa
20 µg/$150
SPON2 / MINDIN Protein
Select
E. coli
6His, N-terminus
38 kDa
10 µg/$265; 50 µg/$315
Select
HEK 293 Cells
6His, N-terminus
33 kDa
100 µg/$298
Select
HEK 293 Cells
6His, N-terminus
33 kDa
200 µl/$283
SPON2 / MINDIN Protein - Recombinant Spondin 2 By SDS-PAGE
Select
E. coli
His-T7
26.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
SPON2 / MINDIN Protein - Recombinant Spondin 2 By SDS-PAGE
Select
E. coli
His-GST
55.2 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
SPON2 / MINDIN Protein - Recombinant Spondin 2 By SDS-PAGE
Select
E. coli
His-T7
26.7 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
SPON2 / MINDIN Protein - 12.5% SDS-PAGE of human SPON2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
59.29 kDa
2 µg/$439
SPON2 / MINDIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
35.6 kDa
100 µg/$494
SPON2 / MINDIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
35.6 kDa
100 µg/$494
Viewing 1-13 of 13 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).