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SPINT1 / HAI-1

serine peptidase inhibitor, Kunitz type 1

SPINT1 / HAI-1 is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.

Gene Name: serine peptidase inhibitor, Kunitz type 1
Family/Subfamily: Serine Protease Inhibitor , not assigned-Serine Protease Inhibitor
Synonyms: SPINT1, HAI1, MANSC2, HAI, HAI-1
Target Sequences: NM_003710 NP_003701.1 O43278

Publications (1)

1
ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion. Aghababaei M, Hogg K, Perdu S, Robinson WP, Beristain AG. Cell death and differentiation. 2015 22:1970-84. (WB; Human) [Full Text Article] [PubMed:25909890] [PMC:PMC4816105] Related Antibodies: LS-C173868.

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).