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SPI1 / PU.1
spleen focus forming virus (SFFV) proviral integration oncogene
Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.
| Gene Name: | spleen focus forming virus (SFFV) proviral integration oncogene |
| Synonyms: | SPI1, 31 kDa-transforming protein, 31 kDa transforming protein, PU.1, SFPI1, SPI-1, SPI-1 proto-oncogene, SPI-A, Transcription factor PU.1 |
| Target Sequences: | NM_003120 NP_003111.2 P17947 |
Publications (2)
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