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SPG21 / MAST

spastic paraplegia 21 (autosomal recessive, Mast syndrome)

SPG21 / MAST binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants.

Gene Name: spastic paraplegia 21 (autosomal recessive, Mast syndrome)
Synonyms: SPG21, ACP33, Acid cluster protein 33, BM-019, Maspardin, GL010, MAST, Spastic paraplegia 21 protein
Target Sequences: NM_016630 NP_057714.1 Q9NZD8

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (6)
Recombinant (7)
SPG21 / MAST (13)
No (13)
GST (2)
GST, N-terminus (1)
His (1)
His-GST (1)
Myc-DDK (Flag) (8)
Human (9)
Mouse (1)
293T Cells (3)
Baculovirus (2)
E. coli (1)
HEK 293 Cells (5)
Wheat Germ Extract (2)
Purified (3)
Low endotoxin level (3)
SPG21 / MAST Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.8 kDa
100 µg/$494
SPG21 / MAST Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
31.4 kDa
100 µg/$494
SPG21 / MAST Protein - 12.5% SDS-PAGE of human SPG21 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
61.4 kDa
10 µg/$479; 25 µg/$670
SPG21 / MAST Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
34.8 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
34.8 kDa
20 µg/$150
SPG21 / MAST Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
31.4 kDa
20 µg/$150
SPG21 / MAST Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.8 kDa
100 µg/$494
SPG21 / MAST Protein - Purified recombinant protein SPG21 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
34.8 kDa
20 µg/$1,107
SPG21 / MAST Protein - Purified recombinant protein SPG21 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
34.8 kDa
20 µg/$1,107
SPG21 / MAST Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Baculovirus
His-GST
Less than 1.0 EU/µg protein (determined by LAL method).
62.8 kDa
100 µg/$843
Select
Baculovirus
GST
Less than 1.0 EU/µg protein (determined by LAL method).
61 kDa
100 µg/$843
SPG21 / MAST Protein
Select
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-13 of 13 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).