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Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase.
Gene Name: | speedy/RINGO cell cycle regulator family member C |
Synonyms: | SPDYC, HSpy/Ringo C, Ringo2, RINGOC, Speedy protein C, RINGO C, Speedy C |
Target Sequences: | NM_001008778 NP_001008778.1 Q5MJ68 |
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