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SPANXC / SPANX-C
SPANX family, member C
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.
| Gene Name: | SPANX family, member C |
| Synonyms: | SPANXC, CTp11, CT11.3, SPANX family member C, SPAN-Xc protein, SPANX family, member C, SPANX-C, Cancer/testis antigen 11.3 |
| Target Sequences: | NM_022661 NP_073152.2 Q9NY87 |
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