SPANXA1

sperm protein associated with the nucleus, X-linked, family member A1

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

SPANXA1 (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human SPANXA1 Protein (Recombinant GST) (Full Length) - LS-G33510

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

37.62 kDa

Price:

10 µg/$479; 25 µg/$670

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SPANXA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114252

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.9 kDa

Price:

100 µg/$494

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Human SPANXA1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69328

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.9 kDa

Price:

20 µg/$1,107

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Human SPANXA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84366

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.9 kDa

Price:

20 µg/$150

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