SPAG6

sperm associated antigen 6

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

SPAG6 (6)

Publications

No (6)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human SPAG6 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71432

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.5 kDa

Price:

20 µg/$1,107

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Human SPAG6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89751

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.5 kDa

Price:

20 µg/$150

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Human SPAG6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89750

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.3 kDa

Price:

20 µg/$215

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Human SPAG6 Protein (Recombinant GST) (Full Length) - LS-G31711

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76.12 kDa

Price:

2 µg/$439

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SPAG6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105491

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.5 kDa

Price:

100 µg/$494

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SPAG6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114428

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.3 kDa

Price:

100 µg/$710

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