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SPAG5 / MAP126

sperm associated antigen 5

Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU.

Gene Name: sperm associated antigen 5
Synonyms: SPAG5, Astrin, DEEPEST, MAP126, Sperm associated antigen 5, Sperm-associated antigen 5, HMAP126
Target Sequences: NM_006461 NP_006452.3 Q96R06

☰ Filters
Products
Antibodies (28)
Primary (28)
SPAG5 / MAP126 (28)
Human (28)
Rat (2)
IHC (4)
IHC-P (2)
WB (25)
ELISA (4)
IF (3)
IP (3)
Peptide-ELISA (1)
rabbit (13)
mouse (15)
IgG (9)
IgG1 (8)
IgG2a (7)
monoclonal mc (15)
polyclonal pc (13)
OTI1F3 (2)
OTI2D6 (2)
OTI2F2 (2)
OTI3F10 (2)
OTI3F9 (1)
OTI5B2 (2)
OTI5H5 (2)
OTI6G2 (2)
Carrier-free (7)
Unconjugated (28)
aa1-297 (15)
aa1-300 (2)
N-Terminus (1)
aa1-50 (1)
aa875-925 (1)
No (28)
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$351
SPAG5 / MAP126 Antibody - Immunohistochemistry of paraffin-embedded human testis using antibody at 1:100 dilution.
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
SPAG5 / MAP126 Antibody - Immunofluorescence analysis of HeLa cell using SPAG5 antibody. Blue: DAPI for nuclear staining.
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SPAG5 / MAP126 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SPAG5 / MAP126 Antibody - Immunohistochemistry of paraffin-embedded human testis using antibody at 1:100 dilution.
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal (aa1-300) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal (aa875-925) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (OTI3F10) Antibody
Human
WB
Unconjugated
100 µl/$434
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPAG5. (1:2000)
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (Carrier-free) (OTI3F10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SPAG5 / MAP126 Antibody - Western blot analysis SPAG5 using Jurkat whole cells lysates
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SPAG5 / MAP126 Antibody - Immunofluorescence analysis of HeLa cells using SPAG5 Polyclonal Antibody.
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (OTI2D6) Antibody
Human
WB
Unconjugated
100 µl/$434
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPAG5. (1:2000)
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (Carrier-free) (OTI2D6) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (OTI1F3) Antibody
Human
WB
Unconjugated
100 µl/$434
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPAG5. (1:2000)
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (Carrier-free) (OTI1F3) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (OTI5B2) Antibody
Human
WB
Unconjugated
100 µl/$434
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPAG5. (1:2000)
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (Carrier-free) (OTI5B2) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (OTI5H5) Antibody
Human
WB
Unconjugated
100 µl/$434
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPAG5. (1:500)
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (Carrier-free) (OTI5H5) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (OTI2F2) Antibody
Human
WB
Unconjugated
100 µl/$434
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPAG5. (1:2000)
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (Carrier-free) (OTI2F2) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (OTI6G2) Antibody
Human
WB
Unconjugated
100 µl/$434
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPAG5. (1:2000)
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (Carrier-free) (OTI6G2) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
SPAG5 / MAP126 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SPAG5. (Right lane) cDNA for 48 hrs and lysed
Select
SPAG5 / MAP126 Mouse anti-Human Monoclonal (aa1-297) (OTI3F9) Antibody
Human
WB
Unconjugated
100 µl/$434
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$725
Select
SPAG5 / MAP126 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$444; 100 µg/$597
Viewing 1-25 of 28 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).