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Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. May play a role in chromatin-mediated regulation of gene expression although it doesn't bind to histone H3 tails.
Gene Name: | SP140 nuclear body protein |
Synonyms: | SP140, Nuclear autoantigen Sp-140, Speckled 140 kDa, LYSP100, SP140 nuclear body protein, LYSP100-A, LYSP100-B, Nuclear body protein SP140 |
Target Sequences: | NM_007237 NP_009168.4 Q13342 |
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