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SOX8
SRY (sex determining region Y)-box 8
SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
| Gene Name: | SRY (sex determining region Y)-box 8 |
| Family/Subfamily: | Transcription factor |
| Synonyms: | SOX8, Transcription factor SOX-8 |
| Target Sequences: | AF164104 CAB75612.1 P57073 |
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