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SOX3

SRY (sex determining region Y)-box 3

Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.

Gene Name: SRY (sex determining region Y)-box 3
Family/Subfamily: Transcription factor
Synonyms: SOX3, GHDX, MRGH, SOXB, Panhypopituitarism, PHPX, Sry-box3, PHP, Transcription factor SOX-3
Target Sequences: NM_005634 NP_005625.2 P41225

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Products
Antibodies (36)
Primary (36)
SOX3 (36)
Human (35)
Mouse (18)
Rat (6)
Bat (6)
Dog (9)
Gibbon (9)
Guinea pig (6)
Monkey (7)
Pig (3)
Rabbit (10)
Rodent (1)
Zebrafish (3)
IHC (8)
IHC-Fr (1)
IHC-P (6)
WB (32)
Flo (1)
ELISA (11)
Peptide-ELISA (2)
rabbit (34)
mouse (1)
goat (1)
Product Group
IHCPlus (2)
IgG (27)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (35)
1F2 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (1)
Unconjugated (16)
aa166-196 (7)
C-Terminus (4)
N-Terminus (4)
aa215-264 (4)
aa80-129 (4)
aa189-218 (1)
aa283-295 (1)
aa413-427 (1)
No (36)
SOX3 Antibody - Anti-SOX3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
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IHC-plus™ SOX3 Antibody (aa413-427) LS-B8332
(4.0) Rating
SOX3 Goat anti-Human Polyclonal (aa413-427) Antibody
Rabbit, Mouse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
SOX3 Antibody - Anti-SOX3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX3 Antibody (aa80-129) LS-B1569
SOX3 Rabbit anti-Human Polyclonal (aa80-129) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SOX3 Antibody - Anti-SOX3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX3 Antibody (aa80-129, HRP) LS-C429343
SOX3 Rabbit anti-Human Polyclonal (aa80-129) (HRP) Antibody
Rabbit, Mouse, Dog, Human, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SOX3 Antibody - Anti-SOX3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX3 Antibody (aa80-129, Biotin) LS-C429342
SOX3 Rabbit anti-Human Polyclonal (aa80-129) (Biotin) Antibody
Rabbit, Mouse, Dog, Human, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SOX3 Antibody - Anti-SOX3 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX3 Antibody (aa80-129, FITC) LS-C429344
SOX3 Rabbit anti-Human Polyclonal (aa80-129) (FITC) Antibody
Rabbit, Mouse, Dog, Human, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SOX3 Antibody - MCF7 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX3 Antibody (C-Terminus) LS-C31061
SOX3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
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SOX3 Antibody (aa283-295) LS-C10298
SOX3 Rabbit anti-Human Polyclonal (aa283-295) Antibody
Rodent, Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
50 µg/$578
SOX3 Antibody - Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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SOX3 Antibody LS-C671274
SOX3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
SOX3 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer tissue using SOX3 Polyclonal Antibody at dilution of 1:50(×200)
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SOX3 Antibody LS-C832646
SOX3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SOX3 Antibody - SOX3 monoclonal antibody (M04), clone 1F2 Western Blot analysis of SOX3 expression in A-431.
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SOX3 Antibody (clone 1F2) LS-C198244
SOX3 Mouse anti-Human Monoclonal (1F2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SOX3 Antibody - SOX3 Antibody (Center P204) western blot of A549 cell line lysates (35 ug/lane). The SOX3 antibody detected the SOX3 protein (arrow).
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SOX3 Antibody (aa189-218) LS-C161401
SOX3 Rabbit anti-Human Polyclonal (aa189-218) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
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SOX3 Antibody (aa166-196) LS-C325285
SOX3 Rabbit anti-Human Polyclonal (aa166-196) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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SOX3 Antibody (aa166-196, Biotin) LS-C270019
SOX3 Rabbit anti-Human Polyclonal (aa166-196) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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SOX3 Antibody (aa166-196, FITC) LS-C270022
SOX3 Rabbit anti-Human Polyclonal (aa166-196) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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SOX3 Antibody (aa166-196, APC) LS-C270018
SOX3 Rabbit anti-Human Polyclonal (aa166-196) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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SOX3 Antibody (aa166-196, Azide-free, HRP) LS-C270023
SOX3 Rabbit anti-Human Polyclonal (aa166-196) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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SOX3 Antibody (aa166-196, PE) LS-C270024
SOX3 Rabbit anti-Human Polyclonal (aa166-196) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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SOX3 Antibody LS-C779727
SOX3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
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SOX3 Antibody LS-C809104
SOX3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SOX3 Antibody - Western blot testing of 1) rat brain, 2) rat heart, 3) mouse brain and 4) mouse heart lysate with SOX3 antibody at 0.5ug/ml. Predicted molecular weight ~45 kDa.
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SOX3 Antibody LS-C782148
SOX3 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
100 µg/$575
SOX3 Antibody - MCF7 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX3 Antibody (N-Terminus) LS-C31059
SOX3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
SOX3 Antibody - MCF7 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX3 Antibody (N-Terminus, Biotin) LS-C437329
SOX3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$442
SOX3 Antibody - SOX3 antibody Western blot of PANC1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX3 Antibody (aa215-264) LS-C109773
SOX3 Rabbit anti-Human Polyclonal (aa215-264) Antibody
Human
WB
Unconjugated
100 µl/$424
SOX3 Antibody - SOX3 Antibody western blot of MDA-MB453,HL-60 cell line lysates (35 ug/lane). The SOX3 antibody detected the SOX3 protein (arrow).
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SOX3 Antibody (aa166-196) LS-C161402
SOX3 Rabbit anti-Human Polyclonal (aa166-196) Antibody
Human
WB
Unconjugated
400 µl/$393
SOX3 Antibody - Western blot analysis of SOX3 using anti-SOX3 antibody. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: rat brain tissue lysates, Lane 2: rat heart tissue lysates, Lane 3: mouse brain tissue lysates, Lane 4: mouse heart tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-SOX3 antigen affinity purified polyclonal antibody at 0.5 ?g/mL overnight at 4?C, then washed with TBS-0.1% Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for SOX3 at approximately 45KD. The expected band size for SOX3 is at 45KD.
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SOX3 Antibody LS-C756542
SOX3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
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