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SOX18

SRY (sex determining region Y)-box 18

SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

Gene Name: SRY (sex determining region Y)-box 18
Family/Subfamily: Transcription factor
Synonyms: SOX18, Transcription factor SOX-18, Sox-8, SRY-box 18, HLTS
Target Sequences: NM_018419 NP_060889.1 P35713

Publications (1)

1
Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer. Jia Y, Cao B, Yang Y, Linghu E, Zhan Q, Lu Y, Yu Y, Herman JG, Guo M. Oncotarget. 2015 6:33470-85. (WB; Human) [Full Text Article] [PubMed:26396173] [PMC:PMC4741779] Related Antibodies: LS-C30068.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
SOX18 (5)
No (5)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (3)
Rat (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
SOX18 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SOX18 Protein - Purified recombinant protein SOX18 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
40.7 kDa
20 µg/$1,107
SOX18 Protein - Recombinant Sex Determining Region Y Box Protein 18 By SDS-PAGE
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E. coli
His-T7
27.2 kDa
50 µg/$512; 10 µg/$292; 200 µg/$1,018; 100 µg/$817; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
SOX18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
40.7 kDa
20 µg/$150
SOX18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.7 kDa
100 µg/$494
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).