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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SOX18

SRY (sex determining region Y)-box 18

SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

Gene Name: SRY (sex determining region Y)-box 18
Family/Subfamily: Transcription factor
Synonyms: SOX18, Transcription factor SOX-18, Sox-8, SRY-box 18, HLTS
Target Sequences: NM_018419 NP_060889.1 P35713

Publications (1)

1
Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer. Jia Y, Cao B, Yang Y, Linghu E, Zhan Q, Lu Y, Yu Y, Herman JG, Guo M. Oncotarget. 2015 6:33470-85. (WB; Human) [Full Text Article] [PubMed:26396173] [PMC:PMC4741779] Related Antibodies: LS-C30068.

Filtered By: None
Target
SOX18 (29)
Reactivity
Human (19)
Mouse (10)
Rat (19)
Bovine (4)
Chimpanzee (6)
Gibbon (6)
Guinea pig (8)
Hamster (4)
Monkey (1)
Pig (8)
Application
IHC (5)
IHC-P (5)
WB (29)
ELISA (9)
ICC (2)
IF (1)
Host
rabbit (29)
Isotype
IgG (24)
Clonality
polyclonal pc (29)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (8)
Epitope
aa153-377 (10)
aa59-88 (8)
aa192-241 (4)
aa271-320 (4)
N-Terminus (1)
Publications
No (28)
Yes (1)
Showing 1-25 of 29 results

SOX18 Antibody IHC-plus™ LS-B3089
Rabbit Polyclonal (IgG) to Human SOX18
Human, Monkey
IHC IHC-P WB
Unconjugated
50µg 0.2mg/ml  $425.00
Anti-SOX18 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-SOX18 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-SOX18 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-SOX18 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

SOX18 Antibody (aa271-320) LS-C30068
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human SOX18
Mouse, Guinea pig, Bovine, Rat, Hamster, Pig, Human
IHC IHC-P WB
Unconjugated
50µg  $365.00
SOX18 antibody ARP33056_P050-NP_060889-SOX18 (SRY (sex determining region Y)-box 18) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Heart Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SOX18 antibody ARP33056_P050-NP_060889-SOX18 (SRY (sex determining region Y)-box 18) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Heart Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SOX18 Antibody (aa271-320, HRP) LS-C428962
Rabbit Polyclonal (IgG) to Human SOX18
Mouse, Guinea pig, Bovine, Rat, Hamster, Pig, Gibbon, Chimpanzee, Human
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
SOX18 antibody ARP33056_P050-NP_060889-SOX18 (SRY (sex determining region Y)-box 18) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Heart Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SOX18 antibody ARP33056_P050-NP_060889-SOX18 (SRY (sex determining region Y)-box 18) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Heart Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SOX18 Antibody (aa271-320, Biotin) LS-C428959
Rabbit Polyclonal (IgG) to Human SOX18
Mouse, Guinea pig, Bovine, Rat, Hamster, Pig, Gibbon, Chimpanzee, Human
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
SOX18 antibody ARP33056_P050-NP_060889-SOX18 (SRY (sex determining region Y)-box 18) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Heart Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SOX18 antibody ARP33056_P050-NP_060889-SOX18 (SRY (sex determining region Y)-box 18) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Heart Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SOX18 Antibody (aa271-320, FITC) LS-C428960
Rabbit Polyclonal (IgG) to Human SOX18
Mouse, Guinea pig, Bovine, Rat, Hamster, Pig, Gibbon, Chimpanzee, Human
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $385.00
SOX18 antibody ARP33056_P050-NP_060889-SOX18 (SRY (sex determining region Y)-box 18) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Heart Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SOX18 antibody ARP33056_P050-NP_060889-SOX18 (SRY (sex determining region Y)-box 18) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Heart Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SOX18 Antibody (aa59-88) LS-C161400
Rabbit Polyclonal to Human SOX18
Human
IF WB
Unconjugated
400µl  $305.00
Fluorescent confocal image of HeLa cell stained with SOX18 Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with SOX18 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). SOX18 immunoreactivity is localized to Nucleus significantly.
SOX18 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The SOX18 antibody detected the SOX18 protein (arrow).
Fluorescent confocal image of HeLa cell stained with SOX18 Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with SOX18 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). SOX18 immunoreactivity is localized to Nucleus significantly.
SOX18 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The SOX18 antibody detected the SOX18 protein (arrow).

SOX18 Antibody (aa59-88) LS-C325283
Rabbit Polyclonal (IgG) to Human SOX18
Human
ELISA WB
Unconjugated
200µl  $530.00

SOX18 Antibody (aa59-88, Biotin) LS-C269997
Rabbit Polyclonal (IgG) to Human SOX18
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

SOX18 Antibody (aa59-88, FITC) LS-C269998
Rabbit Polyclonal (IgG) to Human SOX18
Human
ELISA WB
FITC Conjugated
200µl  $680.00

SOX18 Antibody (aa59-88, Azide-free, HRP) LS-C269999
Rabbit Polyclonal (IgG) to Human SOX18
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

SOX18 Antibody (aa59-88, AP) LS-C269994
Rabbit Polyclonal (IgG) to Human SOX18
Human
ELISA WB
AP Conjugated
200µl  $680.00

SOX18 Antibody (aa59-88, PE) LS-C270000
Rabbit Polyclonal (IgG) to Human SOX18
Human
ELISA WB
PE Conjugated
200µl  $680.00

SOX18 Antibody (aa59-88, APC) LS-C269996
Rabbit Polyclonal (IgG) to Human SOX18
Human
ELISA WB
APC Conjugated
200µl  $680.00

SOX18 Antibody (N-Terminus) LS-C336195
Rabbit Polyclonal (IgG) to Human SOX18
Mouse, Rat, Human
ELISA WB
Unconjugated
100µg 1mg/ml  $365.00
Western blot analysis of SOX18 in 3T3 cell lysate with SOX18 antibody at 1 ug/ml.
Western blot analysis of SOX18 in 3T3 cell lysate with SOX18 antibody at 1 ug/ml.

SOX18 Antibody LS-C406032
Rabbit Polyclonal (IgG) to Human SOX18
Mouse, Human
ELISA WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Western blot analysis of HeLa cell and mouse heart,K562 and Jurkat cell, using SOX18 Polyclonal Antibody at dilution of 1:650.
Western blot analysis of HeLa cell and mouse heart,K562 and Jurkat cell, using SOX18 Polyclonal Antibody at dilution of 1:650.

SOX18 Antibody (aa153-377) LS-C314496
Rabbit Polyclonal (IgG) to Rat SOX18
Rat
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $515.00; 10ml 0.5mg/ml  $2,040.00
Western blot of recombinant SOX18.
Western blot of recombinant SOX18.

SOX18 Antibody (aa153-377, Biotin) LS-C419002
Rabbit Polyclonal (IgG) to Rat SOX18
Rat
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $365.00

SOX18 Antibody (aa153-377, Biotin) LS-C684470
Rabbit Polyclonal (IgG) to Rat SOX18
Rat
WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $560.00; 10ml  $2,250.00
Western blot of recombinant SOX18.
Western blot of recombinant SOX18.

SOX18 Antibody (aa153-377, FITC) LS-C419004
Rabbit Polyclonal (IgG) to Rat SOX18
Rat
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $385.00

SOX18 Antibody (aa153-377, FITC) LS-C690711
Rabbit Polyclonal (IgG) to Rat SOX18
Rat
WB
FITC Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $325.00; 1ml  $620.00; 10ml  $2,460.00
Western blot of recombinant SOX18.
Western blot of recombinant SOX18.

SOX18 Antibody (aa153-377, APC) LS-C738615
Rabbit Polyclonal (IgG) to Rat SOX18
Rat
WB
APC Conjugated
20µl  $225.00; 100µl  $305.00; 200µl  $365.00; 1ml  $770.00
Western blot of recombinant SOX18.
Western blot of recombinant SOX18.

SOX18 Antibody (aa192-241) LS-C30917
Rabbit Polyclonal to Human SOX18
Mouse, Guinea pig, Rat, Pig, Human
WB
Unconjugated
100µg  $325.00
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SOX18 Antibody (aa192-241, HRP) LS-C428963
Rabbit Polyclonal to Human SOX18
Mouse, Guinea pig, Rat, Pig, Gibbon, Chimpanzee, Human
WB
HRP Conjugated
100µl 0.65mg/ml  $335.00
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SOX18 Antibody (aa192-241, Biotin) LS-C428961
Rabbit Polyclonal to Human SOX18
Mouse, Guinea pig, Rat, Pig, Gibbon, Chimpanzee, Human
WB
Biotin Conjugated
100µl 1mg/ml  $335.00
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SOX18 Antibody (aa192-241, FITC) LS-C428964
Rabbit Polyclonal to Human SOX18
Mouse, Guinea pig, Rat, Pig, Gibbon, Chimpanzee, Human
WB
FITC Conjugated
100µl 1mg/ml  $335.00
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 29 results

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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