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SOX10

SRY (sex determining region Y)-box 10

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Gene Name: SRY (sex determining region Y)-box 10
Family/Subfamily: Transcription factor
Synonyms: SOX10, DOM, Transcription factor SOX-10, WS4, PCWH, WS2E, SRY-related HMG-box gene 10, WS4C, SOX-10
Target Sequences: NM_006941 NP_008872.1 P56693

Publications (1)

1
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy. Johnson DB, Estrada MV, Salgado R, Sanchez V, Doxie DB, Opalenik SR, Vilgelm AE, Feld E, Johnson AS, Greenplate AR, Sanders ME, Lovly CM, Frederick DT, Kelley MC, Richmond A, Irish JM, Shyr Y, Sullivan RJ, Puzanov I, Sosman JA, Balko JM. Nature communications. 2016 7:10582. (IHC-P; Human) [Full Text Article] [PubMed:26822383] [PMC:PMC4740184] Related Antibodies: LS-C312170.

☰ Filters
Antibodies (53)
Proteins (7)
ELISA Kits (1)
Custom (1)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Primary (53)
Recombinant (3)
SOX10 (61)
Human (48)
Mouse (12)
Rat (10)
Chimpanzee (3)
Gibbon (3)
Zebrafish (4)
IHC (19)
IHC-Fr (5)
IHC-P (27)
WB (36)
Flo (6)
ELISA (17)
ICC (1)
IF (8)
IP (3)
mIF (1)
Peptide-ELISA (2)
rabbit (30)
mouse (22)
goat (1)
Product Group
IHCPlus (2)
IgG (24)
IgG1 (2)
IgG1,k (2)
IgG2a,k (1)
IgG2b (1)
IgG2b,k (15)
monoclonal mc (22)
polyclonal pc (26)
recombinant monoclonal rmc (5)
1E6 (1)
2E7B5 (1)
2E7E8 (1)
AHC0235 (1)
EP268 (2)
G010.1 (1)
rSOX10/1074 (2)
SBX10-1 (3)
SOX10/1074 (3)
SOX10/2311R (2)
SOX10/991 (3)
SPM607 (2)
96-Well Microplate (1)
APC Conjugated (1)
Azide-free (7)
Biotin Conjugated (3)
BSA-free (4)
Carrier-free (2)
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HRP Conjugated (3)
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aa115-269 (6)
aa238-267 (6)
aa191-240 (4)
aa147-252 (2)
Amino Acids 204-217 (1)
aa1-50 (1)
aa416-466 (1)
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GST (1)
GST, N-terminus (1)
His, N-Terminal (2)
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Human (6)
293T Cells (1)
HEK 293 Cells (4)
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SOX10 Antibody - Anti-SOX10 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SOX10 Mouse anti-Human Monoclonal (1E6) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
SOX10 Antibody - IHC of Cytokeratin SOX-10 on FFPE Melanoma tissue.
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SOX10 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$309
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SOX10 Rabbit anti-Human Polyclonal (aa238-267) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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SOX10 Rabbit anti-Human Polyclonal (aa238-267) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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SOX10 Rabbit anti-Human Polyclonal (aa238-267) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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SOX10 Rabbit anti-Human Polyclonal (aa238-267) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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SOX10 Rabbit anti-Human Polyclonal (aa238-267) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
SOX10 Protein - Purified recombinant protein SOX10 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
49.7 kDa
20 µg/$1,107
SOX10 Antibody - IHC of paraffin-embedded breast cancer tissues using SOX10 mouse monoclonal antibody with DAB staining.
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SOX10 Mouse anti-Human Monoclonal (aa147-252) (2E7E8) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$459
SOX10 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) at 10 µg/ml.
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SOX10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC-P, WB
Unconjugated
0.05 mg/$460
SOX10 Antibody - IHC testing of FFPE human melanoma with SOX10 antibody (clone SOX10/991). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
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SOX10 Mouse anti-Human Monoclonal (SOX10/991) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SOX10 Antibody - IHC testing of FFPE human melanoma with SOX10 antibody (clone SOX10/991). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
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SOX10 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SOX10/991) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
SOX10 Antibody - Western blot using SOX10 monoclonal antibody against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)
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SOX10 Mouse anti-Human Monoclonal (aa147-252) (2E7B5) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
SOX10 Antibody - IHC of SOX-10 on a Frozen Acetone-Fixed Melanoma Tissue
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SOX10 Mouse anti-Human Monoclonal (Ready-to-Use) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$453
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SOX10 Rabbit anti-Human Monoclonal (EP268) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$376; 0.5 ml/$562; 1 ml/$956
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SOX10 Rabbit anti-Human Monoclonal (Ready-to-Use) (EP268) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$411; 7 ml/$620; 15 ml/$899
SOX10 Antibody - Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SPM607).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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SOX10 Mouse anti-Human Monoclonal (aa115-269) (SPM607) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SOX10 Antibody - IHC testing of FFPE human melanoma with SOX-10 antibody (clone SOX10/1074). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
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SOX10 Mouse anti-Human Monoclonal (SOX10/1074) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SOX10 Antibody - IHC testing of FFPE human melanoma with SOX-10 antibody (clone SOX10/1074). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min followed by cooling at RT for 20 min.
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SOX10 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SOX10/1074) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
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SOX10 Rabbit Recombinant Monoclonal Antibody
ICC, IHC, IP, mIF, WB
Unconjugated
10 µl/$299; 100 µl/$548
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SOX10 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
SOX10 Antibody - IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1). Required HIER: boil sections in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
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SOX10 Mouse anti-Human Monoclonal (SBX10-1) Antibody
Human
IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
SOX10 Antibody - IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1). Required HIER: boil sections in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
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SOX10 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SBX10-1) Antibody
Human
IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
SOX10 Antibody - Detection of human SOX10 by immunohistochemistry. Sample: FFPE section of breast carcinoma. Antibody: Rabbit anti-SOX10 antibody (A305-799A-M lot 1) used at 1:200. Secondary: HRP-conjugated goat anti-rabbit IgG (A120-501P). Substrate: DAB.
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SOX10 Rabbit anti-Human Polyclonal (aa416-466) Antibody
Human
IP, WB
Unconjugated
10 µl/$295
SOX10 Antibody - SOX10 antibody IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SOX10 Rabbit anti-Human Polyclonal (aa191-240) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
Viewing 1-25 of 61 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).