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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SOX10

SRY (sex determining region Y)-box 10

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Gene Name: SRY (sex determining region Y)-box 10
Family/Subfamily: Transcription factor
Synonyms: SOX10, DOM, Transcription factor SOX-10, WS4, PCWH, WS2E, SRY-related HMG-box gene 10, WS4C
Target Sequences: NM_006941 NP_008872.1 P56693

Publications (1)

1
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy. Johnson DB, Estrada MV, Salgado R, Sanchez V, Doxie DB, Opalenik SR, Vilgelm AE, Feld E, Johnson AS, Greenplate AR, Sanders ME, Lovly CM, Frederick DT, Kelley MC, Richmond A, Irish JM, Shyr Y, Sullivan RJ, Puzanov I, Sosman JA, Balko JM. Nature communications. 2016 7:10582. (IHC-P; Human) [Full Text Article] [PubMed:26822383] [PMC:PMC4740184] Related Antibodies: LS-C312170.

Filtered By: None
Target
SOX10 (52)
Reactivity
Human (47)
Mouse (10)
Rat (8)
Bat (1)
Bovine (1)
Chicken (1)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Hamster (1)
Horse (1)
Monkey (1)
Pig (1)
Rabbit (1)
Xenopus (1)
Zebrafish (4)
Application
IHC (33)
IHC-Fr (2)
IHC-P (25)
WB (41)
Flo (14)
ELISA (19)
IF (17)
IHC-Fx (4)
Peptide-ELISA (1)
SDS-PAGE (4)
Host
rabbit (24)
mouse (27)
goat (1)
Isotype
IgG (18)
IgG1 (2)
IgG1,k (5)
IgG2a,k (1)
IgG2b,k (17)
Clonality
monoclonal mc (25)
polyclonal pc (23)
recombinant monoclonal rmc (4)
Clone
1E6 (1)
2E7B5 (1)
2E7E8 (1)
ABM42D7 (1)
ABM4E24 (1)
AHC0235 (1)
BSB-62 (1)
IHC010 (2)
rSOX10/1074 (2)
SBX10-1 (3)
SOX10/1074 (3)
SOX10/2311R (2)
SOX10/991 (3)
SOX10/991 + SOX10/1074 (3)
SOX10/992 (2)
SPM607 (2)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (7)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Ready-to-Use (7)
Unconjugated (40)
Epitope
aa115-269 (22)
aa238-267 (7)
aa191-240 (4)
aa147-252 (2)
Amino Acids 204-217 (1)
Publications
No (51)
Yes (1)
Showing 1-25 of 52 results

SOX10 Antibody (clone 1E6) IHC-plus™ LS-B5939
Mouse Monoclonal [clone 1E6] (IgG2a,k) to Human SOX10
Human
ELISA IHC IHC-P WB
Unconjugated
50µg 0.49mg/ml  $485.00
Anti-SOX10 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-SOX10 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-SOX10 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-SOX10 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

SOX10 Antibody LS-C312170
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human SOX10
Human
IHC IHC-Fr IHC-P
Unconjugated
100µl 100µg/ml  $235.00; 500µl 100µg/ml  $315.00; 1000µl 100µg/ml  $455.00
IHC of Cytokeratin SOX-10 on FFPE Melanoma tissue.
IHC of Cytokeratin SOX-10 on FFPE Melanoma tissue.

SOX10 Antibody LS-C10305
Rabbit Polyclonal to Human SOX10
Xenopus, Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
ELISA WB
Unconjugated
50µg 0.55mg/ml  $345.00; 100µg  $465.00

SOX10 Antibody LS-C669022
Rabbit Polyclonal (IgG) to Human SOX10
Human
ELISA IF IHC IHC-P WB
Unconjugated
0.1mg  $365.00
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry of SOX10 in rat heart tissue with SOX10 Antibody at 5 µg/mL.
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry of SOX10 in rat heart tissue with SOX10 Antibody at 5 µg/mL.

SOX10 Antibody (aa115-269, clone SPM607) LS-C390987
Mouse Monoclonal [clone SPM607] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated
20µg 0.2mg/ml  $255.00; 100µg  $395.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SPM607).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SPM607).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SPM607, Azide-free) LS-C390993
Mouse Monoclonal [clone SPM607] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated, Azide-free
100µg 1mg/ml  $415.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SPM607).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SPM607).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/991) LS-C390982
Mouse Monoclonal [clone SOX10/991] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated
20µg 0.2mg/ml  $255.00; 100µg  $395.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/991, Azide-free) LS-C390977
Mouse Monoclonal [clone SOX10/991] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated, Azide-free
100µg 1mg/ml  $415.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/991, Ready-to-Use) LS-C390988
Mouse Monoclonal [clone SOX10/991] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated, Ready-to-Use
7000µl  $395.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody (SOX10/991).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/1074) LS-C390983
Mouse Monoclonal [clone SOX10/1074] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated
20µg 0.2mg/ml  $255.00; 100µg  $395.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein; B) A375 cell lysate using SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein; B) A375 cell lysate using SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/1074, Ready-to-Use) LS-C390980
Mouse Monoclonal [clone SOX10/1074] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated, Ready-to-Use
7000µl  $395.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein; B) A375 cell lysate using SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein; B) A375 cell lysate using SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/1074, Azide-free) LS-C390984
Mouse Monoclonal [clone SOX10/1074] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated, Azide-free
100µg 1mg/ml  $415.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein; B) A375 cell lysate using SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein; B) A375 cell lysate using SOX-10 antibody (SOX10/1074).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/991 + SOX10/1074) LS-C390989
Mouse Monoclonal [clone SOX10/991 + SOX10/1074] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated
20µg 0.2mg/ml  $255.00; 100µg  $395.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/991 + SOX10/1074, Ready-to-Use) LS-C390991
Mouse Monoclonal [clone SOX10/991 + SOX10/1074] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated, Ready-to-Use
7000µl  $395.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/991 + SOX10/1074, Azide-free) LS-C390992
Mouse Monoclonal [clone SOX10/991 + SOX10/1074] (IgG2b,k) to Human SOX10
Human
Flo IF IHC IHC-P WB
Unconjugated, Azide-free
100µg 1mg/ml  $415.00
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein B) A375 cell lysate using SOX10 antibody cocktail.  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SBX10-1) LS-C392039
Mouse Monoclonal [clone SBX10-1] (IgG2b,k) to Human SOX10
Human
IF IHC IHC-P WB
Unconjugated
20µg 0.2mg/ml  $255.00; 100µg  $395.00
IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of 1) partial recombinant protein and 2) A375 cell lysate using SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of 1) partial recombinant protein and 2) A375 cell lysate using SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SBX10-1, Azide-free) LS-C392040
Mouse Monoclonal [clone SBX10-1] (IgG2b,k) to Human SOX10
Human
IF IHC IHC-P WB
Unconjugated, Azide-free
100µg 1mg/ml  $415.00
IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of 1) partial recombinant protein and 2) A375 cell lysate using SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of 1) partial recombinant protein and 2) A375 cell lysate using SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SBX10-1, Ready-to-Use) LS-C392042
Mouse Monoclonal [clone SBX10-1] (IgG2b,k) to Human SOX10
Human
IF IHC IHC-P WB
Unconjugated, Ready-to-Use
7000µl  $395.00
IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of 1) partial recombinant protein and 2) A375 cell lysate using SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
IHC testing of FFPE melanoma with SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of 1) partial recombinant protein and 2) A375 cell lysate using SOX10 antibody (clone SBX10-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa238-267) IHC-plus™ LS-B15581
Rabbit Polyclonal (IgG) to Human SOX10
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
50µl 0.48mg/ml  $425.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.

SOX10 Antibody (aa147-252, clone 2E7E8) LS-C285870
Mouse Monoclonal [clone 2E7E8] (IgG1) to Human SOX10
Human
ELISA IHC WB
Unconjugated
100µg 1mg/ml  $365.00
IHC of paraffin-embedded breast cancer tissues using SOX10 mouse monoclonal antibody with DAB staining.
Western blot using SOX10 monoclonal antibody against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)
IHC of paraffin-embedded breast cancer tissues using SOX10 mouse monoclonal antibody with DAB staining.
Western blot using SOX10 monoclonal antibody against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)

SOX10 Antibody (aa147-252, clone 2E7B5) LS-C285869
Mouse Monoclonal [clone 2E7B5] (IgG1) to Human SOX10
Human
ELISA Flo WB
Unconjugated
100µg  $365.00
Western blot using SOX10 monoclonal antibody against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)
Western blot using SOX10 monoclonal antibody against HEK293 (1) and SOX10 (AA: 147-252)-hIgGFc transfected HEK293 (2) cell lysate.
Western blot using SOX10 monoclonal antibody against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)
Western blot using SOX10 monoclonal antibody against HEK293 (1) and SOX10 (AA: 147-252)-hIgGFc transfected HEK293 (2) cell lysate.

SOX10 Antibody (aa115-269, clone SOX10/992) LS-C390981
Mouse Monoclonal [clone SOX10/992] (IgG1,k) to Human SOX10
Human
Flo IF WB
Unconjugated
20µg 0.2mg/ml  $255.00; 100µg  $395.00
Western blot testing of A) partial recombinant protein and B) A375 cell lysate using SOX10 antibody (SOX10/992).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein and B) A375 cell lysate using SOX10 antibody (SOX10/992).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody (aa115-269, clone SOX10/992, Azide-free) LS-C390986
Mouse Monoclonal [clone SOX10/992] (IgG1,k) to Human SOX10
Human
Flo IF WB
Unconjugated, Azide-free
100µg 1mg/ml  $415.00
Western blot testing of A) partial recombinant protein and B) A375 cell lysate using SOX10 antibody (SOX10/992).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot testing of A) partial recombinant protein and B) A375 cell lysate using SOX10 antibody (SOX10/992).  This image was taken for the unmodified form of this product. Other forms have not been tested.

SOX10 Antibody LS-C751635
Rabbit Polyclonal (IgG) to Human SOX10
Human
ELISA IHC WB
Unconjugated
100µg  $355.00

SOX10 Antibody (aa115-269, clone ABM42D7) LS-C358582
Mouse Monoclonal [clone ABM42D7] (IgG1,k) to Human SOX10
Human
IHC WB
Unconjugated
200µl 0.5mg/ml  $325.00
Showing 1-25 of 52 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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