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SORD / Sorbitol Dehydrogenase

sorbitol dehydrogenase

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Gene Name: sorbitol dehydrogenase
Synonyms: SORD, L-iditol 2-dehydrogenase, SORD1, Sorbitol dehydrogenase
Target Sequences: NM_003104 NP_003095.2 Q00796

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Products
Antibodies (68)
Primary (68)
SORD / Sorbitol Dehydrogenase (68)
Human (49)
Mouse (14)
Rat (11)
Bovine (8)
Chimpanzee (3)
Cow (8)
Dog (3)
Guinea pig (3)
Orangutan (3)
Rabbit (3)
Sheep (1)
IHC (17)
IHC-P (12)
WB (56)
Flo (13)
ELISA (15)
ICC (2)
IF (14)
IP (4)
Peptide-ELISA (2)
rabbit (47)
mouse (20)
goat (1)
Product Group
IHCPlus (2)
IgG (16)
IgG1 (10)
IgG1,k (2)
IgG2a (4)
IgG2b (2)
IgG3 (2)
monoclonal mc (20)
polyclonal pc (48)
4D3 (1)
AT10F4 (1)
OTI12A7 (2)
OTI13G5 (2)
OTI15H2 (2)
OTI17E7 (2)
OTI1D5 (2)
OTI2A10 (2)
OTI4E5 (2)
OTI9E7 (2)
OTI9G9 (2)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (9)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (36)
aa2-357 (8)
aa4-344 (8)
aa98-355 (8)
aa211-239 (7)
aa72-121 (4)
aa1-50 (1)
aa307-357 (1)
aa345-357 (1)
No (68)
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SORD.
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI17E7) Antibody
Human
Flo, IF
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SORD.
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SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI17E7) Antibody
Human
Flo, IF
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SORD.
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SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI1D5) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SORD.
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SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI1D5) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Antibody - IHC of paraffin-embedded breast tissue using anti-SORD mouse monoclonal antibody. (Dilution 1:50).
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI9E7) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - IHC of paraffin-embedded breast tissue using anti-SORD mouse monoclonal antibody. (Dilution 1:50).
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI9E7) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Antibody - IHC of paraffin-embedded breast tissue using anti-SORD mouse monoclonal antibody. (Dilution 1:50).
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI15H2) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - IHC of paraffin-embedded breast tissue using anti-SORD mouse monoclonal antibody. (Dilution 1:50).
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI15H2) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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SORD / Sorbitol Dehydrogenase Goat anti-Human Polyclonal (aa345-357) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
SORD / Sorbitol Dehydrogenase Antibody - Immunoperoxidase of monoclonal antibody to SORD on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1.2 ug/ml]
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SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (4D3) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
SORD / Sorbitol Dehydrogenase Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SORD / Sorbitol Dehydrogenase Antibody - ICC/IF analysis of SORD in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human SORD antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (AT10F4) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
Select
SORD / Sorbitol Dehydrogenase Rabbit anti-Sheep Polyclonal Antibody
Sheep
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
SORD / Sorbitol Dehydrogenase Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SORD / Sorbitol Dehydrogenase Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-SORD mouse monoclonal antibody. (Dilution 1:50).
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI2A10) Antibody
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-SORD mouse monoclonal antibody. (Dilution 1:50).
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI2A10) Antibody
Human
IP, WB
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Antibody - IHC of paraffin-embedded breast tissue using anti-SORD mouse monoclonal antibody. (Dilution 1:50).
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI12A7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SORD.
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI9G9) Antibody
Human
Flo, IF
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SORD.
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI9G9) Antibody
Human
Flo, IF
Unconjugated, Carrier-free
100 µg/$511
SORD / Sorbitol Dehydrogenase Antibody - IHC of paraffin-embedded Ovary tissue using anti-SORD mouse monoclonal antibody. (Dilution 1:50).
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI13G5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - Immunofluorescence analysis of MCF7 cells.
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SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SORD / Sorbitol Dehydrogenase Antibody - Immunofluorescent analysis of Sorbitol Dehydrogenase staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Select
SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SORD.
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (OTI4E5) Antibody
Human
Flo, IF
Unconjugated
100 µl/$434
SORD / Sorbitol Dehydrogenase Antibody - Anti-SORD mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SORD.
Select
SORD / Sorbitol Dehydrogenase Mouse anti-Human Monoclonal (Carrier-free) (OTI4E5) Antibody
Human
Flo, IF
Unconjugated, Carrier-free
100 µg/$511
Select
SORD / Sorbitol Dehydrogenase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
Viewing 1-25 of 68 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).