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SOLO / SESTD1

SEC14 and spectrin domains 1

May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.

Gene Name:	SEC14 and spectrin domains 1
Synonyms:	SESTD1, Protein Solo, SEC14 and spectrin domains 1, SOLO
Target Sequences:	NP_835224.3 Q86VW0

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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