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SOD3

superoxide dismutase 3, extracellular

This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. EC-SOD and iNOS mRNA and protein were expressed in smooth muscle cells and macrophages in early and advanced lesions (Luoma et al., 1998).

Gene Name: superoxide dismutase 3, extracellular
Synonyms: SOD3, EC-SOD
Target Sequences: NM_003102 NP_003093.2 P08294

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Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
SOD3 (10)
No (10)
6His, N-terminus (1)
GST, N-terminus (1)
His (1)
His, N-terminus (1)
His-T7 (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
Rat (2)
293T Cells (1)
E. coli (6)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
SOD3 Protein - Recombinant Superoxide Dismutase 3, Extracellular By SDS-PAGE
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E. coli
His, N-terminus
26.1 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
SOD3 Protein - Recombinant Superoxide Dismutase 3, Extracellular By SDS-PAGE
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E. coli
His-T7, N-terminus
28.6 kDa
10 µg/$270; 50 µg/$372; 100 µg/$592; 200 µg/$742; 1 mg/$1,786; 500 µg/$1,352; 5 mg/$2,742; 2 mg/$1,966
SOD3 Protein - Purified recombinant protein SOD3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.1 kDa
20 µg/$1,107
SOD3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SOD3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
None
1 mg/$1,443; 100 µg/$503; 20 µg/$406
SOD3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
SOD3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
25.88 kDa
20 µg/$150
SOD3 Protein - Recombinant Superoxide Dismutase 3, Extracellular By SDS-PAGE
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E. coli
His-T7
27.9 kDa
10 µg/$274; 50 µg/$400; 100 µg/$637; 200 µg/$797; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053
SOD3 Protein - Recombinant Superoxide Dismutase 3, Extracellular By SDS-PAGE
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E. coli
His
19.1 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
SOD3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
25.88 kDa
100 µg/$494
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).