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SOD2 / Mn SOD

superoxide dismutase 2, mitochondrial

MNSOD / SOD2 is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: superoxide dismutase 2, mitochondrial
Synonyms: SOD2, IPOB, MVCD6, Indophenoloxidase B, Mn superoxide dismutase, MNSOD, Mangano-superoxide dismutase
Target Sequences: NM_000636 NP_000627.2 P04179

Publications (4)

1
A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease. Celotto AM, Liu Z, Vandemark AP, Palladino MJ. Brain and behavior. 2012 2:424-34. (WB; Rat) [Full Text Article] [PubMed:22950046] [PMC:PMC3432965] Related Antibodies: LS-B3694.
2
Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer. Nishio M, Yoneshiro T, Nakahara M, Suzuki S, Saeki K, Hasegawa M, Kawai Y, Akutsu H, Umezawa A, Yasuda K, Tobe K, Yuo A, Kubota K, Saito M, Saeki K. Cell metabolism. 2012 16:394-406. (IHC; Human) [Full Text Article] [PubMed:22958922]
3
Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness. Shetty AK, Attaluri S, Kodali M, Shuai B, Shetty GA, Upadhya D, Hattiangady B, Madhu LN, Upadhya R, Bates A, Rao X. Redox biology. 2020 January;28: [Full Text Article] [PubMed:31778892] [PMC:PMC6888767]
4
Differential structural remodeling of the left-atrial posterior wall in patients affected by mitral regurgitation with or without persistent atrial fibrillation: a morphological and molecular study. Domenico Corradi, Sergio Callegari, Roberta Maestri, David Ferrara, Domenica Mangieri, Rossella Alinovi, Paola Mozzoni, Silvana Pinelli, Matteo Goldoni, Ylenia Adelaide Privitera, Veronica Bartoli, Ettore Astorri, Emilio Macchi, Augusto Vaglio, Stefano Benussi, Ottavio Alfieri. Journal of cardiovascular electrophysiology. 2012 March;23:271-9. [Full Text Article] [PubMed:21954878]
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SOD2 / Mn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$856
SOD2 / Mn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$798
SOD2 / Mn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SOD2 / Mn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SOD2 / Mn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
0.5 - 10 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
SOD2 / Mn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1.87 - 120 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
SOD2 / Mn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Guinea pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Chicken
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SOD2 / Mn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SOD2 / Mn SOD ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
SOD2 / Mn SOD ELISA Kit
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Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
SOD2 / Mn SOD ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SOD2 / Mn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).