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SOD1 / Cu-Zn SOD

superoxide dismutase 1, soluble

SOD1 / Cu-Zn SOD binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Gene Name: superoxide dismutase 1, soluble
Synonyms: SOD1, ALS, ALS1, Cu/Zn superoxide dismutase, HSod1, Homodimer, IPOA, SOD, soluble, SOD, Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, Indophenoloxidase A, Superoxide dismutase, cystolic
Target Sequences: NM_000454 NP_000445.1 P00441

Publications (6)

1
Effect of specific activation of ?-aminobutyric acid receptor in vivo on oxidative stress-induced damage after extended hepatectomy. Gardner LB, Hori T, Chen F, Baine AM, Hata T, Uemoto S, Nguyen JH. Hepatology research : the official journal of the Japan Society of Hepatology. 2012 42:1131-40. (WB; Mouse) [Full Text Article] [PubMed:22583816] [PMC:PMC3438378]
2
Pretreatment of liver grafts in vivo by ?-aminobutyric acid receptor regulation reduces cold ischemia/warm reperfusion injury in rat. Hori T, Gardner LB, Hata T, Chen F, Baine AM, Uemoto S, Nguyen JH. Annals of transplantation : quarterly of the Polish Transplantation Society. 2013 18:299-313. (WB; Rat) [Full Text Article] [PubMed:23792534] [PMC:PMC3912510]
3
Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats. Hori T, Uemoto S, Chen F, Gardner LB, Baine AM, Hata T, Kogure T, Nguyen JH. World journal of hepatology. 2014 6:72-84. (WB; Rat) [PubMed:24575166] [PMC:PMC3934637]
4
Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice. Wang X, Gu H, Huang W, Peng J, Li Y, Yang L, Qin D, Essandoh K, Wang Y, Peng T, Fan GC. Diabetes. 2016 October;65:3111-28. [Full Text Article] [PubMed:27284111] [PMC:PMC5033265]
5
Differential structural remodeling of the left-atrial posterior wall in patients affected by mitral regurgitation with or without persistent atrial fibrillation: a morphological and molecular study. Domenico Corradi, Sergio Callegari, Roberta Maestri, David Ferrara, Domenica Mangieri, Rossella Alinovi, Paola Mozzoni, Silvana Pinelli, Matteo Goldoni, Ylenia Adelaide Privitera, Veronica Bartoli, Ettore Astorri, Emilio Macchi, Augusto Vaglio, Stefano Benussi, Ottavio Alfieri. Journal of cardiovascular electrophysiology. 2012 March;23:271-9. [Full Text Article] [PubMed:21954878]
6
Cardioprotective effects of amiodarone in a rat model of epilepsy-induced cardiac dysfunction. Inas A Harb, Hend Ashour, Abeer Mostafa, Hala M El Hanbuli, Eman Hassan Nadwa. Clinical and experimental pharmacology & physiology. 2022 March;49:406-418. [Full Text Article] [PubMed:34796981]
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SOD1 / Cu-Zn SOD (36)
Human (6)
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Rat (6)
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Plasma (33)
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SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$929
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Monkey
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$745
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
SOD1 / Cu-Zn SOD ELISA Kit
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Development Kit
Antibody Pair and Standard
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,254; 1000 Wells/$1,867
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
1.56 - 100 U/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$929
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Microplate
Pig
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$856
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SOD1 / Cu-Zn SOD ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Pig
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,408; 1000 Wells/$2,123
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Chicken
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
SOD1 / Cu-Zn SOD ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
SOD1 / Cu-Zn SOD ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1 - 25 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
SOD1 / Cu-Zn SOD ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
1 - 25 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
SOD1 / Cu-Zn SOD ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$856
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).