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SNX5 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | sorting nexin 5 |
Synonyms: | SNX5, Sorting nexin-5, Sorting nexin 5 |
Target Sequences: | NM_014426 NP_055241.1 Q9Y5X3 |
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