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SNX3

sorting nexin 3

Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Plays a role in protein transport between cellular compartments. Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G (By similarity). Not involved in EGFR degradation.

Gene Name:	sorting nexin 3
Synonyms:	SNX3, MCOPS8, Sorting nexin 3A, Protein SDP3, SDP3, Sorting nexin-3, Grd19, Sorting nexin 3
Target Sequences:	NM_003795 NP_003786.1 O60493

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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