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SNX2

sorting nexin 2

May be involved in several stages of intracellular trafficking. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).

Gene Name:	sorting nexin 2
Synonyms:	SNX2, Sorting nexin 2, Sorting nexin-2, TRG-9
Target Sequences:	NM_003100 NP_003091.2 O60749

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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