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SNX18

sorting nexin 18

Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.

Gene Name: sorting nexin 18
Synonyms: SNX18, SH3PX2, SH3PXD3B, Sorting nexin 18, SNAG1, Sorting nexin-18
Target Sequences: Q96RF0 Q96RF0

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Products
Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
SNX18 (6)
No (6)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (3)
Mouse (1)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
SNX18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
68.8 kDa
100 µg/$710
SNX18 Protein - Recombinant  Sorting Nexin Associated Golgi Protein 1 By SDS-PAGE
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E. coli
His-T7
27.1 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
SNX18 Protein - Purified recombinant protein SNX18 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
68.8 kDa
20 µg/$1,107
SNX18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
68.8 kDa
20 µg/$215
SNX18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
68.7 kDa
20 µg/$215
SNX18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
68.7 kDa
100 µg/$710
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).