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SNX17

sorting nexin 17

Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).

Gene Name: sorting nexin 17
Synonyms: SNX17, KIAA0064, Sorting nexin-17, Sorting nexin 17
Target Sequences: NM_014748 NP_055563.1 Q15036

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
SNX17 (5)
No (5)
GST (1)
His-S (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
SNX17 Protein - Purified recombinant protein SNX17 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
52.7 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
52.7 kDa
20 µg/$150
SNX17 Protein - 12.5% SDS-PAGE of human SNX17 stained with Coomassie Blue
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Wheat Germ Extract
GST
77.44 kDa
2 µg/$439
SNX17 Protein - Recombinant Sorting Nexin 17 By SDS-PAGE
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E. coli
His-S
29.5 kDa
10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170
SNX17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52.7 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).