SNW1 / SKIP

SNW domain containing 1

Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1. Is involved in NOTCH1-mediated transcriptional activation. Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD. Proposed to be involved in transcriptional activation by EBV EBNA2 of CBF-1/RBPJ-repressed promoters. Is recruited by HIV-1 Tat to Tat:P-TEFb:TAR RNA complexes and is involved in Tat transcription by recruitment of MYC, MEN1 and TRRAP to the HIV promoter. Functions as a splicing factor in pre-mRNA splicing. Is required in the specific splicing of CDKN1A pre-mRNA; the function probbaly involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.

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Antibodies (12)

Type

Primary (12)

Target

SNW1 / SKIP (12)

Reactivity

Human (12)

Mouse (9)

Rat (5)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Hamster (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (3)

Rabbit (3)

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Application

IHC (9)

IHC-P (8)

WB (11)

ELISA (2)

IF (4)

IP (2)

Peptide-ELISA (1)

Host

rabbit (12)

Product Group

IHCPlus (1)

Isotype

IgG (11)

Clonality

polyclonal pc (12)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (9)

Epitope

aa103-152 (4)

aa450-500 (2)

aa464-497 (1)

aa500-C-term (1)

Publications

No (12)

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IHC-plus™ SNW1 / SKIP Antibody LS-B590

(4.0) Rating

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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SNW1 / SKIP Antibody (aa450-500) LS-C287641

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal (aa450-500) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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SNW1 / SKIP Antibody LS-C833333

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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SNW1 / SKIP Antibody (aa500-C-term) LS-C287646

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal (aa500-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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SNW1 / SKIP Antibody LS-C752663

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$351

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SNW1 / SKIP Antibody (aa464-497) LS-C392973

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal (aa464-497) Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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SNW1 / SKIP Antibody (aa103-152) LS-C29711

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal (aa103-152) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$424

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SNW1 / SKIP Antibody (aa103-152, HRP) LS-C427402

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal (aa103-152) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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SNW1 / SKIP Antibody (aa103-152, Biotin) LS-C427174

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal (aa103-152) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SNW1 / SKIP Antibody (aa103-152, FITC) LS-C427175

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal (aa103-152) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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SNW1 / SKIP Antibody (aa450-500) LS-C286442

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal (aa450-500) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

SNW1 / SKIP Antibody LS-C749577

Antibody:

SNW1 / SKIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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