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Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP.
Gene Name: | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa |
Synonyms: | SNRPD2, Sm-D2, SMD2, SnRNP core protein D2 |
Target Sequences: | NM_004597 NP_004588.1 P62316 |
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